Rps15a gene

Author: ssuj

August undefined, 2024

WebFeb 15, 2014 · Ribosomal protein s15a (RPS15A) is a highly conserved protein that promotes mRNA/ribosome interactions early in translation. Recent evidence showed that RPS15A could stimulate growth in yeast, plant and human lung carcinoma. Here we report that RPS15A knockdown could inhibit hepatic cancer cell growth in vitro. WebRPS15a gene primers were designed using Oligo 6.8 (Molecular Bio-logical Insights, Inc., Cascade, CO, USA), and β-actin was used as the reference gene (GenBank accession number: AK225414).

Entry - *603674 - RIBOSOMAL PROTEIN S15a; RPS15A - OMIM

Webrps15a. Predicted to be a structural constituent of ribosome. Involved in several processes, including brain development; chordate embryonic development; and erythrocyte differentiation. Predicted to localize to cytosolic small ribosomal subunit. Human ortholog (s) of this gene implicated in Diamond-Blackfan anemia. WebSep 25, 2024 · The RPS15A gene responds to transforming growth factor beta and facilitates cell proliferation in the A549 cell line of human lung cancer. 76 In addition, … dr matthew hickey

Knockdown of ribosomal protein S15A inhibits proliferation

WebMar 21, 2024 · RPS15A (Ribosomal Protein S15a) is a Protein Coding gene. Diseases associated with RPS15A include Diamond-Blackfan Anemia 20 and Diamond-Blackfan Anemia . Among its related pathways are Peptide chain elongation and Activation of the … GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) is a Protein Coding … WebApr 3, 2015 · RPS15A has been identified as a gene responsible for maintaining the phenotype induced by TGF-β in human lung adenocarcinoma cell line A549 . However, … WebMar 21, 2024 · RPS15 (Ribosomal Protein S15) is a Protein Coding gene. Diseases associated with RPS15 include Leukemia, Chronic Lymphocytic and Insulinoma . Among … dr matthew h etheridge

Rps15a MGI Mouse Gene Detail - MGI:2389091 - ribosomal protein S15A

267019 - Gene ResultRps15a ribosomal protein S15A [ (house …

WebPharos : Target Details - RPS15A Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data WebMay 25, 2024 · Ribosomal protein S15A (RPS15A), as a highly conserved housekeeping gene, encodes a component of 40S ribosomes subunits. At early stages of translation, RPS15A has been shown to promote capped mRNA to bind small ribosomal subunit and modulate ribosome assembly (Jimenez et al. 2004; Shen et al. 2005 ). dr matthew hess far oaks orthopedistsWebJun 1, 2024 · Consistently, RPS15A knockdown significantly impaired the growth of subcutaneous CRC xenografts in nude mice. Conclusions: These results indicate that RPS15A is a novel, potentially oncogenic... coldplay bbc sounds

"WebMaterials and methods: RPS15a mRNA expression was examined in cancer tissues and their corresponding adjacent normal tissues of 40 gastric adenocarcinoma patients. Next, … " - Rps15a gene

Rps15a gene

PSMC2 promotes the progression of gastric cancer via induction …

WebRps15a ribosomal protein S15A [ (house mouse)] Gene ID: 267019, updated on 9-Mar-2024 Summary Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of cell cycle; positive regulation of cell population proliferation; and response to virus. Located in mitochondrion. Webrps15a. Predicted to be a structural constituent of ribosome. Involved in several processes, including brain development; chordate embryonic development; and erythrocyte …

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WebGene summary (Entrez)iUseful information about the gene from Entrez. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Toget her these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a ... WebMar 7, 2024 · RPS15A and mTOR pathway were identified the downstream gene and pathway of PSMC2 by GeneChip and IPA. PSMC2 knockdown inhibited RPS15A expression and mTOR pathway, which was neutralized by...

WebDec 20, 2006 · Within the brain, the telencephalon ( Figure 3A -f) was much smaller than normal in morphants of rps3a, rps4, rps15a, and rpl6, whereas aplasia of the midbrain-hindbrain boundary ( Figure 3A -c) was most prominent in morphants of rps3, rps3a, rps4, rps29, rpl5mix, rpl6, and rpl35a. WebNov 10, 2016 · Because one gene could be categorized into several subcategories, the sum of genes in the subcategories could exceed 100%. GO analysis of the transcriptome revealed nine molecular function subcategories, 62 biological process subcategories, and 12 cellular component subcategories with p value of less than 1 × 10 −5 ) ( Table S2 ).

WebApr 18, 2015 · The hub gene RPS15A, PTGDS, CD53and MSI2might play a vital role in progress of uveal melanoma. CONCLUSION From WGCNA analysis and hub gene calculation, we identified RPS15A, PTGDS, CD53and MSI2might be target or diagnosis for uveal melanoma. Keywords: weighted gene co-expression network analysis, microarray …

WebHuman ortholog(s) of this gene implicated in Diamond-Blackfan anemia 20. Orthologous to human RPS15A (ribosomal protein S15a); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.

WebThe RPS15A mutation observed in the patients led to suppressed cell proliferation in K562 cells. Heterozygous knock-in of the mutation by CRISPR/Cas9 gene editing disturbed pre-rRNA processing for the small subunit. The zebrafish model of RPS15A mutation showed impairment of erythrocyte production. coldplay bbva boletosWebApr 29, 2016 · RPS15A, ribosomal protein s15a, is one of the subunits of the 40S ribosomal protein [ 10, 11 ]. To data, there are several preliminary studies which show that down … dr matthew hewstonWebRPS15A Antibodies Antibodies that detect RPS15A can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation and Flow Cytometry. These antibodies target RPS15A in Human, Mouse and Rat samples. Our RPS15A polyclonal antibodies are developed in Rabbit. Find the RPS15A antibody that fits … coldplay bbk liveWebSequence variants and/or copy number variants (deletions/duplications) within the RPS15A gene will be detected with >99% sensitivity. Variants classified as unknown significance … dr matthew hess fort wayne indianaWebsgRNA-1 targeting eIF3 binding site of RPS15A 5'UTR (RPS15A Human) Use. CRISPR and Lentiviral Tags. Expression. Mutation. Promoter. Availability. Academic Institutions and Nonprofits only Enlarge RPS15A sgRNA-2 lentiCRISPR v2 plasmid. Plasmid #192228. Purpose. lentiviral vector expressing sgRNA-2 targeting eIF3 binding site of RPS15A … dr matthew higginsWebApr 3, 2015 · RPS15A is also a transforming growth factor (TGF) β1-responsive gene and promotes cell proliferation in the A549 lung adenocarcinoma cell line 22 , while RPS15A inhibition impairs the ... dr. matthew hilburn annapolisWebExome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia Exome sequencing identified RPS15A as a novel causative gene for Diamond … dr matthew higgins ortho