WebbCN104203252A CN201380018749.2A CN201380018749A CN104203252A CN 104203252 A CN104203252 A CN 104203252A CN 201380018749 A CN201380018749 A CN 201380018749A CN 104203252 A CN104203252 A CN 104203252A Authority CN China Prior art keywords pirarubicin hydrochlorate maltose injection weight ratio Prior art date … WebbSynthesis of Enzymatically Cleavable Pirarubicin Derivative—N 3-pent-GFLG-Pir N 3 -pent-GFLG-OH was prepared on 2-chlorotrityl chloride resin as described earlier [ 23 ]. …
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WebbThymidylate synthase inhibitors are chemical agents which inhibit the enzyme thymidylate synthase and have potential as an anticancer chemotherapy. [1] This inhibition prevents the methylation of C5 of deoxyuridine monophosphate (dUMP) thereby inhibiting the synthesis of deoxythymidine monophosphate (dTMP). WebbIn this method, synthesis of compound 4 was achieved by applying Eaton’s reagents starting from 2-hydroxybenzoic acid 2 and 1, 3, 5-trihydroxybenzene 3. Compound 5 was synthesized through the O -alkylation reaction, in the presence of K 2 CO 3, KI, and propargyl bromide in acetonitrile at room temperature. dj rosella mp3
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Webb1 jan. 2024 · Pirarubicin anticancer mechanisms are due to DNA intercalation that inhibits DNA and RNA synthesis, inhibition, and stabilization of topoisomerase II complex after breaking the DNA chain, production of double-strand breaks that are not repairable by … Webb21 dec. 2024 · Visit ChemicalBook To find more Pirarubicin(72496-41-4) information like chemical properties,Structure,melting point,boiling point,density,molecular … WebbCN108159005A CN202410134451.2A CN202410134451A CN108159005A CN 108159005 A CN108159005 A CN 108159005A CN 202410134451 A CN202410134451 A CN 202410134451A CN 108159005 A CN108159005 A CN 108159005A Authority CN China Prior art keywords pirarubicin maltose white sugar weight ratio hydrochloride Prior art … dj rossini fbi