Ligustrazine aromatic acid ether derivatives
Netteticylic acid, exhibited interesting neuroprotective activity [15–19]. In our previous effort to develop new neuropro-tective lead compounds, inspired by the potent bioactivi ties of TMP and aromatic acids on neuroprotection, we designed and synthesized several series of ligustrazine derivatives by incorporation of ligustrazine with aromatic acids.
Ligustrazine aromatic acid ether derivatives
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Nettet11. apr. 2024 · Antiplatelet aggregation agents have demonstrated clinical benefits in the treatment of ischemic stroke. In our study, a series of novel nitric oxide (NO)-donating ligustrazine derivatives were designed and synthesized as antiplatelet aggregation agents. They were evaluated for the inhibitory effect on 5′-diphosphate (ADP)-induced … NettetUS-2010228029-A1 chemical patent summary.
Nettet24. sep. 2024 · Carboxylic acids and acid derivatives If a carbonyl carbon is bonded on one side to a carbon (or hydrogen) and on the other side to a heteroatom (in organic chemistry, this term generally refers to oxygen, nitrogen, sulfur, or one of the halogens), the functional group is considered to be one of the ‘ carboxylic acid derivatives’ , a … NettetEP2213666A1 EP08843800A EP08843800A EP2213666A1 EP 2213666 A1 EP2213666 A1 EP 2213666A1 EP 08843800 A EP08843800 A EP 08843800A EP 08843800 A …
NettetMicellar conditions are a new direction of study for ether synthesis as they are simple, efficient, economical and environmentally friendly. 1. Introduction Ethers are a class of organic compounds characterized by an oxygen atom bonded to two alkyl or aryl groups (e.g. R–O–R0). Generally ethers may be categorized as aryl ether, allyl ether, NettetThe invention relates to a tetramethylpyrazine aromatic acid aether type derivative of the general formula (I), a preparation method, drug combinations and applications, wherein, Ar is selected from aryl, substituted aryl or substituted styryl, and R is selected from H or alkyl containing less than six carbon atoms.
NettetDownload scientific diagram Synthesis of the ligustrazine-vanillic acid derivative VA-01–VA-20. Reagents and Conditions: a dry THF, KOH, 4-toluene sulfonyl chloride (Tscl), 25 °C, 15 h; b ...
Nettet28. feb. 2024 · Ligustrazine-vanillic acid derivatives had been reported to exhibit promising neuroprotective activities. In our continuous effort to develop new ligustrazine derivatives with neuroprotective effects, we attempted the synthesis of several ligustrazine-vanillic acid amide derivatives and screened their protective effect on the … paleo thanksgiving sides recipesNettet27. okt. 2008 · Ligustrazine aromatic acid ether derivative, its preparation method, pharmaceutical composition, and application 1 Europe PMC requires Javascript to … paleo thanksgiving turkeyNettet27. okt. 2008 · Europe PMC is an archive of life sciences journal literature. LIGUSTRAZINE AROMATIC ACID ETHER DERIVATIVE, ITS PREPARATION … paleothermometersNettet[origin: EP2213666A1] Ligustrazine aromatic acid ether derivative of general formula I, its preparation method, pharmaceutical composition and application, wherein Ar is … paleothermometre defNettetAccording to different conjunctive positions and numbers of hydroxyls, over 100 novel ligustrazine-phenolic acid derivatives were synthesized and were proved to possess … paleothermometerNettetDownload scientific diagram Synthesis of the ligustrazine-vanillic acid derivative VA-01–VA-20. Reagents and Conditions: a dry THF, KOH, 4-toluene sulfonyl chloride … summing mixer vs itbNettetDownload Table The structures of ligustrazine derivatives L1-21 from publication: Ligustrazinyl amides: A novel class of ligustrazine-phenolic acid derivatives with … summing list elements python