He and klionsky fundc1
Web22 de ene. de 2012 · Here we report that FUNDC1, an integral mitochondrial outer-membrane protein, is a receptor for hypoxia-induced mitophagy. FUNDC1 interacted with LC3 through its typical LC3-binding motif Y... WebFUNDC1 is a membrane protein located in mitochondria. FUNDC1 binds to LC3 through its LIR domain, causing an autophagic bilayer membrane to envelop mitochondria, inducing mitochondrial autophagy. The resulting mitochondrial autophagy inhibits apoptosis and protects neurons.
He and klionsky fundc1
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Web4 de may. de 2016 · Figure 1. FUNDC1 is a novel MAM protein and accumulates in the MAM under hypoxic conditions. Immunoblots of subcellular fractions from HeLa cells exposed to normoxia. P: post-nuclear supernatant; C: cytosol; ER: endoplasmic reticulum; MT: mitochondria; MA: mitochondrial-associated membranes. Web5 de abr. de 2010 · Before that, Klionsky, a California native, was a biology major at UCLA and a graduate student at Stanford, investigating the bacterial ATP synthase with Bob …
http://fund.keyanzhiku.com/Index/info/id/NDI3NDE3MTYwYmllLXNoaS1sZS1xdS1iaWUtcmVuLWppYS1wYS1zaHUtanUtYmE%3D.html Web12 de abr. de 2024 · Abstract. This study aimed to determine if there is an association between mitophagy and refractory temporal lobe epilepsy (rTLE) with hippocampal sclerosis. During epilepsy surgery, we collected tissue samples from the hippocampi and temporal lobe cortexes of rTLE patients with hippocampal sclerosis (as diagnosed by a pathologist).
http://www.chinaqking.com/yc/2024/1114771.html Web5 de dic. de 2024 · FUNDC1 was initially reported to stimulate mitophagy in response to hypoxia. 9 This protein binds to LC3 proteins and operates as an autophagy receptor, and its activity is stimulated by phosphorylation catalyzed by ULK1 10 or by dephosphorylation by PGAM5. 10 In addition, FUNDC1 has been documented to accumulate at …
http://fund.keyanzhiku.com/Index/info/id/NDQ4NzQ5MTQ0YmllLXNoaS1sZS1xdS1iaWUtcmVuLWppYS1wYS1zaHUtanUtYmE%3D.html
Web19 de ene. de 2024 · FUNDC1-knockdown HeLa cells were transfected with FUNDC1-myc for 24 h, and then with plasmids expressing the indicated mitochondria-associated E3 … clod\\u0027s 1nWeb21 de mar. de 2024 · anti-FUNDC1 antibody (FUN14 Domain Containing 1) N-Term. Biorbyt antibodies for FUNDC1. orb1193847. orb1240756. Boster Bio Antibodies for FUNDC1. A08688. Boster Bio Custom Antibody Services (starting from $600), Antibody Validation Service, WB Service, IHC Service, and Multiplex IHC Service. tarjetas fidelidad apple walletWeb10 de dic. de 2024 · FUNDC1 is a new OMM protein that promotes mitochondrial fragmentation and mitophagy during hypoxia ( Liu et al., 2012; Zhang et al., 2016a; … clod\\u0027s 1mWebAnalyzing autophagy in zebrafish Analyzing autophagy in zebrafish Authors Congcong He 1 , Daniel J Klionsky Affiliation 1 Life Sciences Institute and Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA. PMID: 20495344 PMCID: PMC3654832 DOI: 10.4161/auto.6.5.12092 Abstract tarjetas habilitadas midesWebImmunoprecipitation of FUNDC1 protein from A-673 cell extracts. Lane 1 is 10% input, lane 2 is Rabbit (DA1E) mAb IgG XP ® Isotype Control #3900, and lane 3 is FUNDC1 (E2F4T) Rabbit mAb. Western blot analysis was performed using FUNDC1 (E2F4T) Rabbit mAb. Anti-rabbit IgG, HRP-linked Antibody #7074 was used as a secondary antibody. clod\\u0027s 1sWeb23 de feb. de 2024 · PINK1 is a Ser/Thr kinase with a C-terminal kinase domain and N-terminal mitochondrial targeting sequence 55, and PRKN/PARK2 (also known as parkin) … clod\\u0027s 1dWebFUNDC1 regulates receptor-mediated mitophagy independently of the PINK1/Parkin-dependent pathway in rotenone-treated SH-SY5Y cells. Upon mitochondrial stress, … tarjetas inteligentes virtuales tpm